Thames Valley CLRN
The following information has been provided by the TVCLRN:
The TVCLRN will be responsible for facilitating Research Governance approval for all portfolio trials and will work closely with the R&D Department of each member Trust. The TVCLRN is responsible for conducting all governance checks and presenting the result of these checks to the Trust signatory to grant or refuse permission for the research project to take place. A new centralised system for the gaining of NHS permission will be utilised. This will use IRAS as the initial portal interface.
Portfolio trials are those registered on the UKCRN portfolio. Those eligible include those funded by most of the major funding bodies such as the MRC, HTA and the DoH. All researchers are strongly urged to register their trials on the UKCRN portfolio if at all possible.
Future funding and support from the UKCRN through the TVCLRN will only be provided for portfolio studies.
The Oxford University Hospitals NHS Trust is the host Trust for the TVCLRN. To contact the CLRN by telephone, please call (01865) 226637 or email firstname.lastname@example.org.
Adding Studies to the NIHR Portfolio
UKCRN is keen to ensure that all studies which could be eligible for inclusion into the NIHR Portfolio are identified so that they can be supported through the Comprehensive Clinical Research Network. If you are aware of any studies which you think may fulfil the criteria for inclusion in the NIHR Clinical Research Portfolio, and which are not currently listed on the Portfolio Database, we would be very grateful if you would let us know. Further details are available at http://www.ukcrn.org.uk/index/clinical/portfolio_new.html.
Benefit of inclusion in the NIHR Portfolio
Inclusion in the NIHR Portfolio of studies ensures your study can access NHS Service Support Costs and NHS research infrastructure support in England (i.e. support to help with study promotion, approval, identification of eligible patients, recruitment, and follow up etc).
Researchers will be responsible for uploading accrual on a monthly basis to the UKCRN. They will also need to fill out an initial proforma for adoption onto the Portfolio. For further information, see http://www.ukcrn.org.uk.
This support has begun to flow through the Comprehensive Clinical Research Network (CCRN) and an additional activity-based allocation will be made available to the CCRN Local Research Networks from 2008/09. Activity-based funding will be driven by the data which are held on the UKCRN Portfolio Database and it is therefore essential that your study record is kept up-to-date. Once your study has been included, please contact the UKCRN as soon as possible via email (email@example.com) if any changes are required.
Collecting your accrual data
In order to ensure that your study remains on the NIHR Portfolio and receives the appropriate level of support though the relevant Local Research Networks, the UKCRN Coordinating Centre must collect accrual data for the above study from April 2007 and then each month on an ongoing basis.
We have developed a standard format for collecting such data and would be happy to work with you to put this system in place for your study. The minimum information we require is the name of the study, a unique study identifier for each subject recruited (e.g. patient trial number), the site from which the subject was recruited (i.e. name of hospital, not the Trust), and date the subject was recruited.
Subsequent accrual data can be supplied via the UKCRN Accrual Upload System and we will contact you once your study has been accepted to talk you through using this process. Further information and data templates for uploading accrual data can also be found on the UKCRN website at: